Ember LifeSciences raises $16.5M to scale its cold chain cube

Ember LifeSciences debuts Ember Cube 2 following $16.5 million funding raise

Ember Cube 2 shifts to a scalable passive design with advanced insulation optimized for home delivery (Photo: Ember LifeSciences)
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Key Takeaways:

  • Ember LifeSciences secured $16.5 million in Series A funding to expand its connected cold-chain technology for pharmaceutical logistics.
  • The company addresses costly temperature excursions by offering real-time temperature tracking and mid-transit intervention capabilities for high-value medication shipments.
  • Ember is scaling its updated, lighter, and reusable container design for high-volume patient deliveries, anticipating growing demand from home-based care and decentralized clinical trials.
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Ember LifeSciences is moving quickly to turn fresh capital into cold-chain scale. The healthcare logistics technology company has raised $16.5 million in a Series A round to expand deployment of its connected pharmaceutical shipping containers, betting that tighter temperature control and real-time visibility can eliminate one of the industry’s most persistent and costly problems.

Temperature excursions cost the pharmaceutical supply chain an estimated $35 billion annually, a figure that continues to grow as high-value therapies move closer to the patient.

The round was led by Sea Court Capital with participation from strategic healthcare and logistics investors including Cardinal Health and Carrier Ventures, signaling confidence that Ember’s technology can scale beyond pilots and into national healthcare networks.

Unlike traditional cold-chain packaging that relies on estimated hold times and static assumptions, Ember’s platform tracks temperature continuously from origin to destination. That visibility allows shippers to intervene when something goes wrong, rather than discovering losses after the fact. Brian Bejarano, chief commercial officer at Ember LifeSciences, said, “The bigger risk is not the failures the industry identifies, but the ones it never sees, when patients unknowingly receive compromised medication.”

That ability to act mid-transit is where Ember believes its return on investment becomes clear. Bejarano pointed to a pharmacy shipment mistakenly delivered to the wrong address hundreds of miles from its intended destination. Using Ember’s system, the pharmacy generated a new label while the shipment was still in the field, arranged an overnight pickup through FedEx, and recovered the medication before it spoiled. The value saved in that single shipment, he said, outweighed a year’s worth of packaging costs.

Much of the Series A capital will go toward scaling the company’s second-generation container, which was redesigned based on customer feedback. While the original Ember Cube included onboard refrigeration and was often used for store-to-store transfers or multi-stop routes, the second generation, shifts to a lighter, configurable passive platform built specifically for high-volume patient deliveries.

The updated design uses advanced insulation and bio-based phase change materials, while still maintaining Bluetooth and GPS connectivity. The goal is to reduce complexity for pharmacies and patients while preserving the ability to prove temperature compliance at delivery. Ember says the approach also addresses sustainability concerns, as reusable containers significantly reduce the single-use packaging waste that dominates pharmaceutical logistics today.

Early adoption by major healthcare players including CVS Health has helped validate the model as Ember prepares for broader U.S. rollouts. Looking ahead, the company plans to use the funding to support patient-focused solutions slated for 2026, as home-based care and decentralized clinical trials drive demand for verifiable, last-mile cold-chain performance.

As pharmaceutical distribution continues shifting closer to the home, Ember LifeSciences is positioning its technology as infrastructure rather than optional add-on. Bejarano expects that in the coming years, payers and regulators will increasingly require always-on temperature tracking for high-value drugs, making proof of thermal integrity a standard expectation rather than a differentiator.

Mary O'Connell

Former pricing analyst, supply chain planner, and broker/dispatcher turned creator of the newsletter and podcast Check Call. Which gives insights into the world around 3PLs and Freight brokers. She will talk your ear off about anything and everything if you let her. Expertise in operations, LTL pricing and procurement, flatbed operations, dry van, tracking and tracing, reality tv shows and how to turn a stranger into your new best friend.